Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (C-Term) Peptide
TCF7
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183051
Quick Overview for Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (C-Term) Peptide (ABIN2183051)
Target
TCF7
(Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- AKYYELARKE RQLHMQLYPG WSARDNYGKK KRRSREKHQE STTDNSLHYS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCF7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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Background
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The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TCF-1
Protein Size: 365 -
Molecular Weight
- 40 kDa
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Gene ID
- 6932
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NCBI Accession
- NM_213648, NP_998813
Target
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