Adrenergic, beta-1-, Receptor (ADRB1) (C-Term) Peptide
Quick Overview for Adrenergic, beta-1-, Receptor (ADRB1) (C-Term) Peptide (ABIN2183178)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- SDDDDDDVVG ATPPARLLEP WAGCNGGAAA DSDSSLDEPC RPGFASESKV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADRB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
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Background
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ADRB1 is a beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. It mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.
Alias Symbols: ADRB1R, B1AR, BETA1AR, RHR
Protein Size: 477 -
Molecular Weight
- 52 kDa
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Gene ID
- 153
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NCBI Accession
- NM_000684, NP_000675
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UniProt
- P08588
Target
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