Activity-Regulated Cytoskeleton-Associated Protein (Arc) (C-Term) Peptide
Arc
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183421
Quick Overview for Activity-Regulated Cytoskeleton-Associated Protein (Arc) (C-Term) Peptide (ABIN2183421)
Target
Arc
(Activity-Regulated Cytoskeleton-Associated Protein (Arc))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- RHPLPKTLEQ LIQRGMEVQD DLEQAAEPAG PHLPVEDEAE TLTPAPNSES
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))
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Background
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ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. It is required for homeostatic synaptic scaling of AMPA receptors. ARC plays a role in the regulation of cell morphology and cytoskeletal organization and is required in the stress fiber dynamics and cell migration.
Alias Symbols: Arg3.1
Protein Size: 396 -
Molecular Weight
- 43 kDa
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Gene ID
- 23237
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NCBI Accession
- NM_015193, NP_056008
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UniProt
- Q7LC44
Target
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