HEN1 Methyltransferase Homolog 1 (HENMT1) (N-Term) Peptide
HENMT1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HENMT1 products
- HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RETAIQFKPP LYRQRYQFVK NLVDQHEPKK VADLGCGDTS LLRLLKVNPC
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HENMT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))
- Background
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HENMT1 is a methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Alias Symbols: C1orf59, HEN1
Protein Size: 393 - Molecular Weight
- 43 kDa
- Gene ID
- 113802
- NCBI Accession
- NM_144584, NP_653185
- UniProt
- Q5T8I9
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