HEN1 Methyltransferase Homolog 1 (HENMT1) (N-Term) Peptide
HENMT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2184615
Quick Overview for HEN1 Methyltransferase Homolog 1 (HENMT1) (N-Term) Peptide (ABIN2184615)
Target
HENMT1
(HEN1 Methyltransferase Homolog 1 (HENMT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- RETAIQFKPP LYRQRYQFVK NLVDQHEPKK VADLGCGDTS LLRLLKVNPC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HENMT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))
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Background
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HENMT1 is a methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Alias Symbols: C1orf59, HEN1
Protein Size: 393 -
Molecular Weight
- 43 kDa
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Gene ID
- 113802
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NCBI Accession
- NM_144584, NP_653185
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UniProt
- Q5T8I9
Target
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