HEN1 Methyltransferase Homolog 1 (HENMT1) (C-Term) Peptide
HENMT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2184616
Quick Overview for HEN1 Methyltransferase Homolog 1 (HENMT1) (C-Term) Peptide (ABIN2184616)
Target
HENMT1
(HEN1 Methyltransferase Homolog 1 (HENMT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- QVESLRVSHL PRRKEQAGER GDKPKDIGGS KAPVPCFGPV FTEVEKAKIE
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Characteristics
- This is a synthetic peptide designed for use in combination with antiHENMT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at 20C. Avoid repeat freezethaw cycles.
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- HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))
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Background
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HENMT1 is a methyltransferase that adds a 2'Omethyl group at the 3'end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicerindependent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Alias Symbols: C1orf59, HEN1
Protein Size: 393 -
Molecular Weight
- 44 kDa
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Gene ID
- 113802
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NCBI Accession
- NM_144584, NP_653185
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UniProt
- Q5T8I9
Target
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