Paired Box 8 (PAX8) (Middle Region) Peptide
Quick Overview for Paired Box 8 (PAX8) (Middle Region) Peptide (ABIN2185325)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- YSINGLLGIA QPGSDKRKMD DSDQDSCRLS IDSQSSSSGP RKHLRTDAFS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAX8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PAX8 (Paired Box 8 (PAX8))
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Background
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PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.
Protein Size: 450 -
Molecular Weight
- 48 kDa
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Gene ID
- 7849
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UniProt
- Q06710
Target
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