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Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptide

ALOX5AP Reactivity: Human Host: Rabbit BP

Catalog No. ABIN2763850

Quick Overview for Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptide (ABIN2763850)

Target

ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Origin

Human

Source

Rabbit

Application

Blocking Peptide (BP)

Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (C-Term) peptide
ALOX5AP Reactivity: Human Host: Synthetic BP, Imm

Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Internal Region) peptide
ALOX5AP Reactivity: Human, Dog Host: Synthetic BP, Imm

Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Intermediate Domain) peptide
ALOX5AP Reactivity: Human Host: Synthetic BP, BI

Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (C-Term) peptide
ALOX5AP Reactivity: Human Host: Synthetic BP, BI

Restrictions

For Research Use only
Storage

-80 °C
Target

ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Background

Seems to be required for the activation of 5-LO (5-lipoxygenase). Could play an essential role in the transfer of arachidonic acid to 5-LO. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. Genetic variations in FLAP may be a cause of susceptibility to ischemic stroke [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.

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