Amyloid beta (Abeta) (AA 1-40) Peptide
Abeta
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- Target See all beta Amyloid (Abeta) products
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- Protein Region
- AA 1-40
- Purity
- > 95 %
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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- Target
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- Background
- Beta-amyloid peptide (beta-APP) is a 40-residue peptide implicated in the pathogenesis of Alzheimer's disease (AD) and aged Down's Syndrome, which is promoted by the acquisition of an additional copy of chromosome 21. The peptide is a proteolytic product of the much larger amyloid precursor protein (APP) encoded by a gene on chromosome 21. The peptide comprises a large extracellular N-terminal domain and a short hydrophobic membrane-spanning domain, followed by a short C-terminal region. Beta-APP both precedes and forms part of the transmembrane region.
- CAS-No
- 131438-79-4
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