Amyloid beta (Abeta) (AA 1-42) Peptide
Abeta
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- Target See all beta Amyloid (Abeta) products
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- Protein Region
- AA 1-42
- Purity
- > 95 %
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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- Target
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- Background
- This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the -onger forms-of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.
- CAS-No
- 107761-42-2
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