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Amyloid beta (Abeta) (AA 25-35) Peptide

Abeta

(1 reference)

Catalog No. ABIN399149

Quick Overview for Amyloid beta (Abeta) (AA 25-35) Peptide (ABIN399149)

Target

beta Amyloid (Abeta) (Amyloid beta (Abeta))

Protein Region

AA 25-35

Purity

> 95 %
Amyloid beta (Abeta) (AA 1-40) peptide
Abeta

Amyloid beta (Abeta) (AA 1-42) peptide
Abeta Reactivity: Human

Amyloid beta (Abeta) (AA 1-40) peptide
Abeta

Amyloid beta (Abeta) (AA 1-42) peptide
Abeta Reactivity: Human Host: Synthetic

Amyloid beta (Abeta) (AA 1-42) peptide
Abeta

Amyloid beta (Abeta) peptide
Abeta Reactivity: Mouse Host: Synthetic BP, Imm

Amyloid beta (Abeta) (AA 1-16) peptide
Abeta Host: Synthetic BP, Imm

Amyloid beta (Abeta) (AA 1-42) peptide
Abeta Reactivity: Human Host: Synthetic

Amyloid beta (Abeta) peptide
Abeta Reactivity: Human, Pig, Dog, Monkey, Cow Host: Synthetic BP

Amyloid beta (Abeta) peptide
Abeta Reactivity: Human, Pig, Mouse, Rat, Monkey Host: Synthetic BP

Restrictions

For Research Use only
Storage

-20 °C
Bermejo-Bescós, Martín-Aragón, Jiménez-Aliaga, Ortega, Molina, Buxaderas, Orellana, Csákÿ: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." in: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
Target

beta Amyloid (Abeta) (Amyloid beta (Abeta))

Background

Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca2+ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein.

CAS-No

131602-53-4

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