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Epithelial Cell Adhesion Molecule (EPCAM) (N-Term) Peptide

EPCAM Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511055

Quick Overview for Epithelial Cell Adhesion Molecule (EPCAM) (N-Term) Peptide (ABIN5511055)

Target

EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Origin

Human

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    GRRAKPEGAL QNNDGLYDPD CDESGLFKAK QCNGTSMCWC VNTAGVRRTD

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-EPCAM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

    Background

    This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

    Alias Symbols: EPCAM,GA733-2,M1S2,M4S1,MIC18,TACSTD1,TROP1,

    Protein Size: 314

    Gene ID

    4072

    NCBI Accession

    NP_002345

    UniProt

    P16422
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