Epithelial Cell Adhesion Molecule (EPCAM) (N-Term) Peptide
EPCAM
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EpCAM (EPCAM) products
- EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GRRAKPEGAL QNNDGLYDPD CDESGLFKAK QCNGTSMCWC VNTAGVRRTD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EPCAM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
- Background
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This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Alias Symbols: EPCAM,GA733-2,M1S2,M4S1,MIC18,TACSTD1,TROP1,
Protein Size: 314 - Gene ID
- 4072
- NCBI Accession
- NP_002345
- UniProt
- P16422
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