Centrosomal Protein 290kDa (CEP290) (N-Term) Peptide
CEP290
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511068
Quick Overview for Centrosomal Protein 290kDa (CEP290) (N-Term) Peptide (ABIN5511068)
Target
CEP290
(Centrosomal Protein 290kDa (CEP290))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- EQLCQDIIDY QKQIDSQKET LLSRRGEDSD YRSQLSKKNY ELIQYLDEIQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CEP290 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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Background
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This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
Alias Symbols: CT87, MKS4, POC3, rd16, BBS14, JBTS5, LCA10, NPHP6, SLSN6, 3H11Ag
Protein Size: 805 -
Gene ID
- 80184
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NCBI Accession
- NM_025114, NP_079390
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UniProt
- Q05BJ6
Target
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