Sirtuin 3 (SIRT3) (N-Term) Peptide
SIRT3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511098
Quick Overview for Sirtuin 3 (SIRT3) (N-Term) Peptide (ABIN5511098)
Target
SIRT3
(Sirtuin 3 (SIRT3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- AAAPSFFFSS IKGGRRSISF SVGASSVVGS GGSSDKGKLS LQDVAELIRA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SIR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Sirtuin 3 (SIRT3) peptide
SIRT3 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIRT3 (Sirtuin 3 (SIRT3))
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Background
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This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
Alias Symbols: SIRT3,SIR2L3,
Protein Size: 399 -
Gene ID
- 23410
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NCBI Accession
- NP_036371
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UniProt
- Q9NTG7
Target
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