Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) (C-Term) Peptide
Quick Overview for Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) (C-Term) Peptide (ABIN5511230)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- EPSEAGDAPP DDGPPGELGP DGPDGPEEKG RDRDRERRRS HRSERERRRD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RU17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
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Background
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RU17 is a component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Alias Symbols: SNRNP70,RNPU1Z, RPU1, SNRP70, U1AP1,
Protein Size: 437 -
Gene ID
- 6625
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NCBI Accession
- NP_003080
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UniProt
- P08621
Target
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