Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) Peptide
IL1RAP
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511305
Quick Overview for Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) Peptide (ABIN5511305)
Target
IL1RAP
(Interleukin 1 Receptor Accessory Protein (IL1RAP))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LVQYKAVKET KVKELKRAKT VLTVIKWKGE KSKYPQGRFW KQLQVAMPVK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL1RAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
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Background
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Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
Alias Symbols: IL1R3, C3orf13, IL-1RAcP
Protein Size: 570 -
Gene ID
- 3556
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NCBI Accession
- NM_001167928, NP_001161400
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UniProt
- Q9NPH3
Target
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