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Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) (N-Term) Peptide

IDH3B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511310
$160.46
Plus shipping costs $50.00
100 μg
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Quick Overview for Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) (N-Term) Peptide (ABIN5511310)

Target

IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Origin

Human

Source

  • 8
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    RIAKFAFDYA TKKGRGKVTA VHKANIMKLG DGLFLQCCEE VAELYPKIKF

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-IDH3B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

    Background

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

    Protein Size: 233

    Gene ID

    3420
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