MyoD Family Inhibitor (MDFI) (Middle Region) Peptide
MDFI
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511381
Quick Overview for MyoD Family Inhibitor (MDFI) (Middle Region) Peptide (ABIN5511381)
Target
MDFI
(MyoD Family Inhibitor (MDFI))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MDFI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MDFI (MyoD Family Inhibitor (MDFI))
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Background
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This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Alias Symbols: MDFI,
Protein Size: 246 -
Gene ID
- 4188
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NCBI Accession
- NP_005577
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UniProt
- Q99750
Target
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