Paired Box 3 (PAX3) (C-Term) Peptide
Quick Overview for Paired Box 3 (PAX3) (C-Term) Peptide (ABIN5511428)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- SSAYCLPSTR HGFSSYTDSF VPPSGPSNPM NPTIGNGLSP QVPFIISSQI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAX3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Paired Box 3 (PAX3)
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Background
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This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Alias Symbols: PAX3,HUP2,
Protein Size: 403 -
Gene ID
- 5077
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NCBI Accession
- NP_852126
Target
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