PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1) (Middle Region) Peptide
PMS1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511444
Quick Overview for PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1) (Middle Region) Peptide (ABIN5511444)
Target
PMS1
(PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- PFQNDMHNDE SGKNTDDCLN HQISIGDFGY GHCSSEISNI DKNTKNAFQD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- PMS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
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Background
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This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
Alias Symbols: MLH2, PMSL1, hPMS1, HNPCC3
Protein Size: 932 -
Gene ID
- 5378
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NCBI Accession
- NM_000534, NP_000525
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UniProt
- P54277
Target
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