Syndecan 1 (SDC1) (N-Term) Peptide
SDC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Syndecan 1 (SDC1) products
- Syndecan 1 (SDC1)
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LWLWLCALAL SLQPALPQIV ATNLPPEDQD GSGDDSDNFS GSGAGALQDI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- SDC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Syndecan 1 (SDC1)
- Background
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The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Alias Symbols: SDC, CD138, SYND1, syndecan
Protein Size: 310 - Gene ID
- 6382
- NCBI Accession
- NM_001006946, NP_001006947
- UniProt
- P18827
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