Syndecan 1 (SDC1) (N-Term) Peptide
Quick Overview for Syndecan 1 (SDC1) (N-Term) Peptide (ABIN5511574)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- LWLWLCALAL SLQPALPQIV ATNLPPEDQD GSGDDSDNFS GSGAGALQDI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- SDC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Syndecan 1 (SDC1)
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Background
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The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Alias Symbols: SDC, CD138, SYND1, syndecan
Protein Size: 310 -
Gene ID
- 6382
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NCBI Accession
- NM_001006946, NP_001006947
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UniProt
- P18827
Target
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