Ubiquitination Factor E4A (UBE4A) (C-Term) Peptide
UBE4A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UBE4A products
- UBE4A (Ubiquitination Factor E4A (UBE4A))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LAYARQASSQ ECIDVLLQYG CPDERFVLMA TPNLSRRNNN RNNSSGRVPT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- UBE4A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBE4A (Ubiquitination Factor E4A (UBE4A))
- Background
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This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: E4, UFD2, UBOX2
Protein Size: 1066 - Gene ID
- 9354
- NCBI Accession
- NM_001204077, NP_001191006
- UniProt
- Q14139
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