Cadherin 11 (CDH11) (C-Term) Peptide
Quick Overview for Cadherin 11 (CDH11) (C-Term) Peptide (ABIN5511801)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- YDSIQIYGYE GRGSVAGSLS SLESATTDSD LDYDYLQNWG PRFKKLADLY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CDH11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
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Background
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This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Alias Symbols: OB, CAD11, CDHOB, OSF-4
Protein Size: 796 -
Gene ID
- 1009
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NCBI Accession
- NM_001308392, NP_001788
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UniProt
- P55287
Target
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