Cysteinyl-tRNA Synthetase (CARS) (N-Term) Peptide
CARS
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511809
Quick Overview for Cysteinyl-tRNA Synthetase (CARS) (N-Term) Peptide (ABIN5511809)
Target
CARS
(Cysteinyl-tRNA Synthetase (CARS))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- ADSSGQQAPD YRSILSISDE AARAQALNEH LSTRSYVQGY SLSQADVDAF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CARS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARS (Cysteinyl-tRNA Synthetase (CARS))
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Background
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CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. CARS gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Protein Size: 831 -
Gene ID
- 833
Target
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