Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) (C-Term) Peptide
GRIK2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511875
Quick Overview for Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) (C-Term) Peptide (ABIN5511875)
Target
GRIK2
(Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- YEIRLVEDGK YGAQDDANGQ WNGMVRELID HKADLAVAPL AITYVREKVI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GRIK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))
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Background
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.
Protein Size: 548 -
Gene ID
- 2898
Target
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