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DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1) (C-Term) Peptide

DNAJA1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511880

Quick Overview for DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1) (C-Term) Peptide (ABIN5511880)

Target

DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    SPDKLSLLEK LLPERKEVEE TDEMDQVELV DFDPNQERRR HYNGEAYEDD

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- DNAJA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))

    Background

    This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes.

    Alias Symbols: DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSJ-2, HSPF4, NEDD7, hDJ-2

    Protein Size: 397

    Gene ID

    3301

    NCBI Accession

    NM_001539, NP_001530

    UniProt

    P31689
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