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2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) Peptide

OAS1 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN5512106

Quick Overview for 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) Peptide (ABIN5512106)

Target

OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

C-Term

Sequence

AESNSADDET DDPRRYQKYG YIGTHEYPHF SHRPSTLQAA STPQAEEDWT

Characteristics

This is a synthetic peptide designed for use in combination with anti-OAS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) peptide
OAS1 Host: Synthetic BP, Imm

2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) peptide
OAS1 Host: Synthetic BP, WB, IHC

2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) peptide
OAS1 Host: Synthetic BP, WB, IHC

2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) peptide
OAS1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) peptide
OAS1 Reactivity: Human Host: Synthetic BP, WB, IHC

2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (Middle Region) peptide
OAS1 Reactivity: Human Host: Synthetic BP, WB, IHC

2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (N-Term) peptide
OAS1 Reactivity: Human Host: Synthetic BP, WB, IHC

2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) peptide
OAS1 Reactivity: Human Host: Synthetic BP, WB, IHC

2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) peptide
OAS1 Reactivity: Human Host: Synthetic BP, BI

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Background

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.

Alias Symbols: OAS1, OIAS,

Protein Size: 400

Gene ID

4938

NCBI Accession

NP_058132

UniProt

P00973

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