BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) Peptide
BIK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512171
Quick Overview for BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) Peptide (ABIN5512171)
Target
BIK
(BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- SEVRPLSRDI LMETLLYEQL LEPPTMEVLG MTDSEEDLDP MEDFDSLECM
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BIK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
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Background
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The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
Alias Symbols: BIK,NBK,
Protein Size: 160 -
Gene ID
- 638
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NCBI Accession
- NP_001188
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UniProt
- Q13323
Target
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