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Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (C-Term) Peptide

CPT1A Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512241
  • Target See all CPT1A products
    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    RQAYFGRGKN KQSLDAVEKA AFFVTLDETE EGYRSEDPDT SMDSYAKSLL
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CPT1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
    Background
    The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CPT1A,CPT1,

    Protein Size: 773
    Gene ID
    1374
    NCBI Accession
    NP_001867
    UniProt
    P50416
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