N-Myc Downstream Regulated 1 (NDRG1) (C-Term) Peptide
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- Target See all NDRG1 products
- NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SLDGTRSRSH TSEGTRSRSH TSEGTRSRSH TSEGAHLDIT PNSGAAGNSA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NDRG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
- Background
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This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: GC4, RTP, DRG1, NDR1, NMSL, TDD5, CAP43, CMT4D, DRG-1, HMSNL, RIT42, TARG1, PROXY1
Protein Size: 394 - Gene ID
- 10397
- NCBI Accession
- NM_001135242, NP_001128714
- UniProt
- Q92597
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