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N-Myc Downstream Regulated 1 (NDRG1) (C-Term) Peptide

NDRG1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512312

Quick Overview for N-Myc Downstream Regulated 1 (NDRG1) (C-Term) Peptide (ABIN5512312)

Target

NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Origin

Human

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    SLDGTRSRSH TSEGTRSRSH TSEGTRSRSH TSEGAHLDIT PNSGAAGNSA

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-NDRG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

    Background

    This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Alias Symbols: GC4, RTP, DRG1, NDR1, NMSL, TDD5, CAP43, CMT4D, DRG-1, HMSNL, RIT42, TARG1, PROXY1

    Protein Size: 394

    Gene ID

    10397

    NCBI Accession

    NM_001135242, NP_001128714

    UniProt

    Q92597
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