N-Myc Downstream Regulated 1 (NDRG1) (C-Term) Peptide
Quick Overview for N-Myc Downstream Regulated 1 (NDRG1) (C-Term) Peptide (ABIN5512312)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- SLDGTRSRSH TSEGTRSRSH TSEGTRSRSH TSEGAHLDIT PNSGAAGNSA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NDRG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
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Background
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This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: GC4, RTP, DRG1, NDR1, NMSL, TDD5, CAP43, CMT4D, DRG-1, HMSNL, RIT42, TARG1, PROXY1
Protein Size: 394 -
Gene ID
- 10397
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NCBI Accession
- NM_001135242, NP_001128714
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UniProt
- Q92597
Target
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