Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) Peptide
S1PR1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512329
Quick Overview for Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) Peptide (ABIN5512329)
Target
S1PR1
(Sphingosine-1-Phosphate Receptor 1 (S1PR1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- KCPSGDSAGK FKRPIIAGME FSRSKSDNSS HPQKDEGDNP ETIMSSGNVN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- S1PR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
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Background
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The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.
Alias Symbols: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362
Protein Size: 382 -
Gene ID
- 1901
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NCBI Accession
- NM_001400, NP_001391
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UniProt
- P21453
Target
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