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Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (Middle Region) Peptide

IRAK3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512385

Quick Overview for Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (Middle Region) Peptide (ABIN5512385)

Target

IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    EDDESQNNNL LPSDEGLRID RMTQKTPFEC SQSEVMFLSL DKKPESKRNE

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- IRAK3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

    Background

    This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.

    Alias Symbols: ASRT5, IRAKM

    Protein Size: 596

    Gene ID

    11213

    NCBI Accession

    NM_001142523, NP_001135995

    UniProt

    Q9Y616
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