Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Middle Region) Peptide
PIK3CA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512434
Quick Overview for Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Middle Region) Peptide (ABIN5512434)
Target
PIK3CA
(Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- IIVVIWVIVS PNNDKQKYTL KINHDCVPEQ VIAEAIRKKT RSMLLSSEQL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PIK3CA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
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Background
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Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
Alias Symbols: MCM, CWS5, MCAP, PI3K, CLOVE, MCMTC, p110-alpha
Protein Size: 1608 -
Gene ID
- 5290
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NCBI Accession
- NM_006218, NP_006209
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UniProt
- P42337
Target
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