Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72) Peptide
VPS72
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512502
Quick Overview for Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72) Peptide (ABIN5512502)
Target
VPS72
(Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-VPS72 antibody (Catalog #: ARP74345_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
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Background
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The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Alias Symbols: TCFL1, YL1
Protein Size: 364 -
Molecular Weight
- 40 kDa
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Gene ID
- 6944
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NCBI Accession
- NP_005988
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UniProt
- Q15906
Target
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