Methyl-CpG Binding Domain Protein 4 (MBD4) (Middle Region) Peptide
MBD4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512590
Quick Overview for Methyl-CpG Binding Domain Protein 4 (MBD4) (Middle Region) Peptide (ABIN5512590)
Target
MBD4
(Methyl-CpG Binding Domain Protein 4 (MBD4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TSLKPEDFDF TVLSKRGIKS RYKDCSMAAL TSHLQNQSNN SNWNLRTRSK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- MBD4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))
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Background
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The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: MED1
Protein Size: 580 -
Gene ID
- 8930
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NCBI Accession
- NM_001276270, NP_001263199
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UniProt
- O95243
Target
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