Chitotriosidase (CHIT1) (C-Term) Peptide
CHIT1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Chitotriosidase 1 (CHIT1) products
- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GTPELEVPKP GQPSEPEHGP SPGQDTFCQG KADGLYPNPR ERSSFYSCAA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CHIT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
- Background
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Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Alias Symbols: CHI3, CHIT, CHITD
Protein Size: 466 - Gene ID
- 1118
- NCBI Accession
- NM_001256125, NP_001243054
- UniProt
- Q13231
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