Chitotriosidase (CHIT1) (C-Term) Peptide
CHIT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512621
Quick Overview for Chitotriosidase (CHIT1) (C-Term) Peptide (ABIN5512621)
Target
Chitotriosidase 1 (CHIT1)
(Chitotriosidase (CHIT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequence
- GTPELEVPKP GQPSEPEHGP SPGQDTFCQG KADGLYPNPR ERSSFYSCAA
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti- CHIT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
-
Background
-
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Alias Symbols: CHI3, CHIT, CHITD
Protein Size: 466 -
Gene ID
- 1118
-
NCBI Accession
- NM_001256125, NP_001243054
-
UniProt
- Q13231
Target
-
You are here:
