Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) Peptide
Quick Overview for Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) Peptide (ABIN5512630)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- AGGGDDLGAP DELLAFQDEG EEQDDKSRDS AAGPERDLAE LKSSLVNESE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCF7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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Background
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The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.
Protein Size: 365 -
Gene ID
- 6932
Target
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