ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) Peptide
ADAM17
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512714
Quick Overview for ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) Peptide (ABIN5512714)
Target
ADAM17
(ADAM Metallopeptidase Domain 17 (ADAM17))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- DGFEKDPFPN SSTAAKSFED LTDHPVTRSE KAASFKLQRQ NRVDSKETEC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADAM17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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Background
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This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.
Alias Symbols: ADAM17,CSVP,TACE,
Protein Size: 824 -
Gene ID
- 6868
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NCBI Accession
- NP_003174
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UniProt
- P78536
Target
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