Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (Middle Region) Peptide
ACE
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512722
Quick Overview for Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (Middle Region) Peptide (ABIN5512722)
Target
Angiotensin I Converting Enzyme 1 (ACE)
(Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- DINFLMKMAL DKIAFIPFSY LVDQWRWRVF DGSITKENYN QEWWSLRLKY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACE Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
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Background
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This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.
Alias Symbols: DCP, ICH, ACE1, DCP1, CD143, MVCD3
Protein Size: 1306 -
Gene ID
- 1636
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NCBI Accession
- NM_000789, NP_000780
Target
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