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ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) (Middle Region) Peptide

ARFGAP3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512915
  • Target See all ARFGAP3 products
    ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    TSDMQTIEQE SPIMAKPRKK YNDDSDDSYF TSSSSYFDEP VELRSSSFSS
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- ARFGAP3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
    Background
    The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.

    Alias Symbols: ARFGAP1

    Protein Size: 472
    Gene ID
    26286
    NCBI Accession
    NM_001142293, NP_001135765
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