Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptide
CDKN1C
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512971
Quick Overview for Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptide (ABIN5512971)
Target
CDKN1C
(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- ELSRELQARL AELNAEDQNR WDYDFQQDMP LRGPGRLQWT EVDSDSVPAF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CDKN1C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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Background
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This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: BWS, WBS, p57, BWCR, KIP2, p57Kip2
Protein Size: 316 -
Gene ID
- 1028
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NCBI Accession
- NM_000076, NP_000067
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UniProt
- P49918
Target
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