Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (C-Term) Peptide
mTOR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513010
Quick Overview for Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (C-Term) Peptide (ABIN5513010)
Target
MTOR (mTOR)
(Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- PLLNWRLMDT NTKGNKRSRT RTDSYSAGQS VEILDGVELG EPAHKKTGTT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MTOR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
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Background
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The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Alias Symbols: SKS, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Protein Size: 161 -
Gene ID
- 2475
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NCBI Accession
- NP_004949
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UniProt
- B1AKQ2
Target
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