Fascin (FSCN1) (Middle Region) Peptide
FSCN1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Fascin (FSCN1) products
- Fascin (FSCN1)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PIIVFRGEHG FIGCRKVTGT LDANRSSYDV FQLEFNDGAY NIKDSTGKYW
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- FSCN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Fascin (FSCN1)
- Background
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This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
Alias Symbols: HSN, SNL, p55, FAN1
Protein Size: 493 - Gene ID
- 6624
- NCBI Accession
- NM_003088, NP_003079
- UniProt
- Q16658
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