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Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Middle Region) Peptide

GRIA4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5513033

Quick Overview for Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Middle Region) Peptide (ABIN5513033)

Target

GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-GRIA4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

    Background

    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.

    Alias Symbols: GRIA4,GLUR4,

    Protein Size: 433

    Gene ID

    2893
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