Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (C-Term) Peptide
HGS
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513052
Quick Overview for Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (C-Term) Peptide (ABIN5513052)
Target
HGS
(Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- YNMQNLMTTL PSQDASLPPQ QPYIAGQQPM YQQMAPSGGP PQQQPPVAQQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- HGS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
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Background
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The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.
Alias Symbols: HRS
Protein Size: 777 -
Gene ID
- 9146
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NCBI Accession
- NM_004712, NP_004703
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UniProt
- O14964
Target
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