Lysine (K)-Specific Demethylase 4C (KDM4C) (C-Term) Peptide
KDM4C
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KDM4C products
- KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LMPYHKPDSS NEENDARWET KLDEVVTSEG KTKPLIPEMC FIYSEENIEY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KDM4C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
- Background
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This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Alias Symbols: KDM4C,GASC1, JHDM3C, JMJD2C, KIAA0780,
Protein Size: 813 - Gene ID
- 23081
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