Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) Peptide
LCK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513090
Quick Overview for Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) Peptide (ABIN5513090)
Target
LCK
(Lymphocyte-Specific Protein tyrosine Kinase (LCK))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP LQDNLVIALH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LCK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
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Background
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LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
Protein Size: 363 -
Gene ID
- 3932
Target
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