ElaC Homolog 2 (ELAC2) (C-Term) Peptide
ELAC2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513198
Quick Overview for ElaC Homolog 2 (ELAC2) (C-Term) Peptide (ABIN5513198)
Target
ELAC2
(ElaC Homolog 2 (ELAC2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- ITCNPEEFIV EALQLPNFQQ SVQEYRRSAQ DGPAPAEKRS QYPEIIFLGT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ELAC2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ELAC2 (ElaC Homolog 2 (ELAC2))
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Background
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The protein encoded by this gene has a C-terminal domain with tRNA 3′, processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Size: 501 -
Gene ID
- 60528
Target
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