MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3) (N-Term) Peptide
MYST3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513421
Quick Overview for MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3) (N-Term) Peptide (ABIN5513421)
Target
MYST3
(MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GLDRKTVLEQ LELSVKDGTI LKVSNKGLNS YKDPDNPGRI ALPKPRNHGK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MYST3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))
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Background
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This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with autosomal dominant mental retardation-32. Alternative splicing results in multiple transcript variants.
Alias Symbols: MOZ, MRD32, MYST3, MYST-3, ZNF220, RUNXBP2, ZC2HC6A
Protein Size: 815 -
Gene ID
- 7994
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NCBI Accession
- NM_006766, NP_006757
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UniProt
- A5PLL3
Target
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