MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Middle Region) Peptide
MRE11A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513422
Quick Overview for MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Middle Region) Peptide (ABIN5513422)
Target
Mre11 (MRE11A)
(MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequence
- ATNKGRGRGR GRRGGRGQNS ASRGGSQRGR ADTGLETSTR SRNSKTAVSA
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti- MRE11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
-
Background
-
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: ATLD, HNGS1, MRE11, MRE11B
Protein Size: 708 -
Gene ID
- 4361
-
NCBI Accession
- NM_005590, NP_005581
-
UniProt
- P49959
Target
-
You are here:
