Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (Middle Region) Peptide
PELI1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513515
Quick Overview for Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (Middle Region) Peptide (ABIN5513515)
Target
Pellino 1 (PELI1)
(Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SMKRKDVVDE KQPWVYLNCG HVHGYHNWGN KEERDGKDRE CPMCRSVGPY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- PELI1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
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Background
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E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation.
Protein Size: 418 -
Gene ID
- 57162
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NCBI Accession
- NM_020651, NP_065702
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UniProt
- Q96FA3
Target
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